Cerebral Venous Thrombosis and Sickle Cell (SC) Disease

Ðe brain scan will be completed by a cerebral angioIRM which showed a thrombosis of the superior sagittal sinus. Biological tests including NFS-VS revealed anemia with a hemoglobin level of 10 g/dl and a hematocrit of 22%. Ðe white line and platelets were normal. VS was at 20 mmH1. Electrophoresis of hemoglobin conÙ½rmed the following proportions of hemocyte S, 50% hemoglobin S and 50% hemoglobin C. Finally, a coagulation balance comprising the determination of antiphospholipid antibodies, homocysteine, prothrombin and factor V Leiden was negative. Ðe patient was put on eوٴective anticoagualtion low molecular weight heparin for two weeks and then relayed by bone Xarel to 20 mg/d for 165 days. Ðe evolution was simple for both fracture and cerebral venous thrombosis. Radiological examination of the leg showed a consolidated fracture at three months. A phleboscanner test at one month showed a complete disappearance of thrombosis.